Emoxypine Succinate
CAS No. 127464-43-1
Emoxypine Succinate( —— )
Catalog No. M21129 CAS No. 127464-43-1
Emoxypine Succinate is an antioxidant.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameEmoxypine Succinate
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NoteResearch use only, not for human use.
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Brief DescriptionEmoxypine Succinate is an antioxidant.?
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DescriptionEmoxypine Succinate is an antioxidant.?(In Vitro):Emoxypine succinate shows reactive oxygen species overproduction and disruption of the mitochondrial inner membrane due to the decreasing of transmembrane potential.(In Vivo):Emoxypine succinate (i.p.; 40 mg/kg; 1 time per day, 14 days) decreases the production of reactive oxygen species, mitochondrial transmembrane potential percentage of leukocyte and the percentage of FITC Annexin V- positive cells of leukocyte suspension.
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In VitroEmoxypine succinate shows reactive oxygen species overproduction and disruption of the mitochondrial inner membrane due to the decreasing of transmembrane potential.
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In VivoEmoxypine succinate (i.p.; 40 mg/kg; 1 time per day, 14 days) decreases the production of reactive oxygen species, mitochondrial transmembrane potential percentage of leukocyte and the percentage of FITC Annexin V- positive cells of leukocyte suspension. Animal Model:Rats Dosage:40 mg/kg Administration:Intraperitoneal, 1 time per day, 14 days Result:Significantly increased the percentage of Annexin V-positive cells, reduced the apoptotic percentage of white blood cells and decreased the production of reactive oxygen species by leukocytes.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptorothers
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Research AreaCardiovascular Disease
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IndicationIschemic Stroke
Chemical Information
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CAS Number127464-43-1
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Formula Weight255.27
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Molecular FormulaC8H11NO.C4H6O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 250 mg/mL (979.36 mM)
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SMILESCCc1nc(C)ccc1O.O=C(O)CCC(=O)O
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Chemical Name2-Ethyl-6-methylpyridin-3-ol Succinate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Pashin E N Shvedova A A . [The effect of the synthetic antioxidant emoxypine on the tonus of the coronary vessels][J]. farmakologiia i toksikologiia 1989 52(5):17-19.
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